Table 1.
Endogenous ligands | Healthy tissue | Patient tumor samples | Cancer cell lines |
---|---|---|---|
HDL LDL VLDL OxLDL AcLDL Lipid-free apolipoproteins (apoA-I, apoA-II, apoC-II, apoE2, apoE3, apoE4) Serum amyloid A LPS Vitamin E (Calvo et al., 1997; Xu et al., 1997; Liadaki et al., 2000; Thuahnai et al., 2003; Vishnyakova et al., 2003; Baranova et al., 2005; Reboul et al., 2006) |
Liver Steroidogenic tissues (testis, ovaries, adrenals) Brain Small and large intestine Platelets (Acton et al., 1996; Husemann and Silverstein, 2001; Lobo et al., 2001; Imachi et al., 2003) |
Adrenal tumors Breast cancer Lymphoma Nasopharyngeal carcinoma Pancreatic cancer Prostate cancer Prostate bone metastasis Testicular cancer (Imachi et al., 1999; Arenas et al., 2004; Cao et al., 2004; Thysell et al., 2010; Yang et al., 2013; Zheng et al., 2013; Schorghofer et al., 2015; Julovi et al., 2016; Yuan et al., 2016) |
Adrenocortical: NCI-H295R Brain: SK-N-MC, MC-IXC, SK-KN-DW, 1321N1, U87 Breast: MDA-231, MDA (MB) 231, MCF7, P-148, Bone, 361, T4TD, T470, SK-Br-3 Colorectal: RKO, SWA480, SW620, HCT116, IGROV Epithelial: KB Ovarian: HIO-160, HeyA8, HeyA8-MDR, SKOV3ip1, OV 1063 Leukemia: THP-1,MT2, NB4, NB4 0076/6, MT1 Liver: HepG2, HUH-7, HF1 Lung: A549 Lymphoma: LY3, SUDHL-4, SUDHL-6, Farage, Ramos, Farage, Raji, Namalwa, Daudi, Jeko, HH, Hut-78 Nasopharyngeal: 6-10B, SUNE1, CNE2, CNE1, SUNE2, 5-8F, Pancreatic: Aspc1, L3-6PL, Panc48, Panc1, MIAPaCa-2, CFPAC-1 and BxPC3 Prostate: 22RVI, PC3, LnCap, DU145 Testicular: R2C (Lacko et al., 2002; Rao, 2002; Pilon et al., 2003; Wadsack et al., 2003; Cao et al., 2009; Fletcher et al., 2010; Shahzad et al., 2011; Shin et al., 2012; Yang et al., 2013; Zheng et al., 2013; Julovi et al., 2016) |