Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2016 Sep 27;7:1466. doi: 10.3389/fmicb.2016.01466

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2016 Santos, Silva, Silva, Rodrigues, Grisotto, Correia, Napoleão, Silva, Paiva.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

PMC Copyright notice

Overview of applications of “omics technologies” to evaluate the mechanisms of action of natural antimicrobials (NAM). (A) Genomic approaches: the target can be discovered by comparing the DNA sequence of a NAM-resistant bacteria and normal bacteria. (B) Proteomic and transcriptomic approaches: target identification can be performed by evaluating differential expression of genes in strains treated or untreated with NAM. (C) Metabolomic analysis: the metabolic profile of a bacterium treated with NAM can be compared with the profile of different drugs with known actions, potentially leading to target identification.