Table 4.

Comparison of image-guided biopsy modalities

Biopsy method	Compression	Patient position	Advantages	Limitations
US-guided	No	Supine	Real time verification of needle position, fast, no ionizing radiation, low costs	Not useful for MC/distortions
Stereotactic	Yes	Upright/prone	Useful for MC/distortions, sample verification ex vivo possible (MC)	Ionizing radiation
MRI-guided	Yes	Prone	Useful for US and MG occult lesions, no ionizing radiation	High costs, long procedure time, limitation in claustrophobia, obesity and renal insufficiently, sample verification ex vivo not possible
MBI-guided	Yes (mild)	Upright	Useful for indeterminate/unclear lesions on MG/US, sample verification ex vivo possible	Lesions close to the pectoral muscle, ionizing radiation, long procedure time

US ultrasound, MRI magnetic resonance imaging, MG mammography, MBI molecular breast imaging, MC microcalcifications