Figure 2.

Brain clearance of radiolabeled Aβ species. (A) Clearance of monomeric (black bars) and oligomeric (gray bars) [¹²⁵I]Aβ1-40 species removed from the brain at three different time-points. (B) Monomeric (black bars) and oligomeric (gray bars) [¹²⁵I]Aβ1-40 species cleared to the CSF evaluated at three different time-points. In all cases bars illustrate percentage cleared relative to total injected radioactivity; values represent mean ± SD obtained from inoculation of 5–7 mice (ANOVA and Tukey post-hoc test; ns, not significant; ^*p < 0.05; ^**p < 0.01; ^***p < 0.001).