Table 2.
The decreased regional VMHC in LOD group relative to HCs.
| Brain regions | BA | Voxel number | Coordinates MNI | T-score | ||
|---|---|---|---|---|---|---|
| X | Y | Z | ||||
| LOD < HCs: | ||||||
| Superior frontal gyrus | 10 | 100 | 6 | 21 | 57 | −5.34 |
| Superior temporal gyrus | 22 | 74 | 51 | −6 | 3 | −5.46 |
| Cerebellum posterior lobe | / | 117 | 45 | −63 | −36 | −5.13 |
| Postcentral gyrus | 2/3 | 65 | 27 | −24 | 66 | −4.95 |
| Precentral gyrus | 4 | 56 | 17 | −29 | 73 | −5.07 |
Abbreviations: VHMC, Voxel-Mirrored Homotopic Connectivity; LOD, Late-Onset Depression; HCs, Healthy Controls; BA, Brodmann Area; MNI coordinates, Montreal Neurological Institute coordinates of the peak voxel; T, the statistical value of the peak intensity voxel; 1 voxel = 3 mm × 3 mm × 3 mm. The MNI coordinates of peak voxel are symmetrical as the VMHC computation bases on the symmetrical template.