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Model for formation of the qacC' fragment present in Types Ia and IIa plasmids. A single nt insertion 137 nt downstream of qacC (indicated by the asterisk) is present in some Type II plasmids (e.g., pLUH01) and conserved in both Types Ia and IIa. This is evidence that the duplication of the 142 nt-long qacC' fragment, inserted at position −45, occurred in a Type II plasmid to form Type IIa, after which the complete locus was mobilized to give Type Ia.
