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. 2015 May 4;13(5):584–592. doi: 10.1038/cmi2015.36

Figure 5.

Figure 5

Effect of ebosin on the production of MMPs and chemokines mediated by IL-1β in FLSs. (a, b) Inhibition of ebosin on the production of MMP1 and MMP3. The levels of MMP1 and MMP3 were determined using ELISA. (c, d) Effects of ebosin on the expression of chemokines, including RANTES and IL-8. The expression levels of RANTES and IL-8 were determined through ELISA. These data are expressed as the mean ± SD from at least three independent experiments. P < 0.001, P < 0.01 and P < 0.05 compared with the respective control (FLS incubated with IL-1β).