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. 2015 Jun 8;13(5):593–604. doi: 10.1038/cmi.2015.39

Figure 5.

Figure 5

LSK pretreated with Wnt5a gave rise to reduced DC in vivo. CD45.2+ LSK with or without Wnt5a treatment were transferred into lethally irradiated CD45.1+ mice. CDP in the BM and DC in the spleens of chimeric mice were analyzed 4 weeks after transplantation. (A) The plots show the percentages of CDP in the BM of chimeric mice, and the graphs summarize the percentages and cell numbers of CDP. (B) The plots show the percentages of DC subsets in the spleens of chimeric mice, and the graphs summarize the percentages and cell numbers of DC subsets. Data are representative of three independent experiments, each including 58 mice. Error bars represent SEM (*P < 0.05, **P < 0.01, ***P < 0.001).