Table 4.

Examples of thermozymes isolated by sequence-based screening of metagenomes.

Enzyme	Source of metagenomic DNA	References
Cellulase	Long-term dry thermophilic methanogenic digester	Wang et al., 2015
Xylanase	Cow dung compost	Sun et al., 2015
Xylanase	Long-term dry thermophilic methanogenic digester	Wang et al., 2015
Endoxylanase	Compost	Dougherty et al., 2012
β-galactosidase	Hot spring water, Yongtai	Liu et al., 2015
β-xylosidase/α-arabinofuranosidase	Compost	Dougherty et al., 2012
β-xylosidase	Long-term dry thermophilic methanogenic digester	Wang et al., 2015
Pectinase	Hot spring soil, Manikaran, India	Singh et al., 2012
α-fucosidase	Compost	Dougherty et al., 2012
Phytase (phosphatase)	Insect-cultivated fungus gardens	Tan et al., 2016
Limonene 1,2-epoxide hydrolase	Hot springs water	Ferrandi et al., 2015
Nitrilase	Atlantis II Deep Brine Pool, Red Sea	Sonbol et al., 2016
α-amylase	Hydrotermal vent, Juan de la Fuca	Wang et al., 2011
Dehidroclorinase	Soil contaminated with HCH-isomers	Macwan et al., 2011
Polymerase	Hot spring 3173 Pol	Moser et al., 2012