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IF2 in 30S PICs, Related to Figure 6
(A) Space filling model of PIC-I, II and III. IF2 is in the same position and conformation in all PICs.
(B) Superposition of the crystal structure of Thermus IF2 (PDB: 4KJZ; Eiler et al., 2013) on IF2 in PIC-III shows the large movement of domain C1 (curved arrow) upon binding to the 30S. The small arrow shows the loop after helix8 of C1 domain that interacts with IF1 in this new conformation on 30S.
