Table 3.
Reliability and agreement of the baseline and post-blue pupil diameter and the two PIPR outcome parameters when comparing the previously established protocol both to the condition with the same blue light intensity with a natural pupil as well as to a condition with intensified blue light and a natural pupil.
| Parameter | 160My+ − 160My− | 160My+ − 550My− | ||
|---|---|---|---|---|
| ICC (95% CI) | Bland-Altman Bias (95% Limits of Agreement) | ICC (95% CI) | Bland-Altman Bias (95% Limits of Agreement) | |
| Baseline | 0.88 (0.71–0.95) | −0.06 (−0.84 to 0.73) | 0.92 (0.80–0.97) | −0.05 (−0.72 to 0.62) |
| Post-Blue | 0.03 (−0.42–0.47) | −1.10 (−2.40 to 0.91) | 0.77 (0.50–0.91) | −0.20 (−0.87 to 0.48) |
| PIPR-mm | −0.12 (−0.54–0.35) | 1.04 (−0.54 to 2.62) | 0.67 (0.32–0.86) | 0.15 (−0.84 to 1.14) |
| PIPR-% | −0.27 (−0.64–0.21) | 17.83 (−5.36 to 41.01) | 0.58 (0.19–0.82) | 2.96 (−9.97 to 15.89) |
PIPR, Post-Illumination Pupil Response; ICC, Intraclass Correlation Coefficient; 160My+, 160 µW/cm2 blue light with Mydriatics; 160My−, 160 µW/cm2 blue light with natural pupil; 550My−, intensified blue light (550 µW/cm2 blue light) with natural pupil; In Bland-Altman bias the 160My+ minus 160My− and 160My+ minus 550My−.