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(A–G) β2GPI deficient mice had a significant increase in plasma inflammatory cytokines at 2 h and 6 h time points following LPS challenge. (A) TNFα at 2 h (B) TNFα at 6 h. For IL-6, IFNγ, MIP-1α, MIP-1β and Eotaxin (C–G) at 6 h. (□) = WT = Wild Type mice, (■) = β2GPI−/− = β2-glycoprotein I deficient mice. Mann-Whitney test n = 5 *p < 0.05, **p < 0.01, ***p < 0.001.
