Figure 5. JMJD8 deficiency promotes TNF-induced apoptosis.

(a) Control and JMJD8 knockdown HEK293T cells were treated with either 10 ng/ml of TNFα alone or together with 5 μg/ml of Cyclohexamide (CHX) for 12 hours. Total cell lysates were prepared and immunoblotted with the indicated antibodies (n = 3). Full-length blots are presented in Supplementary Fig. S11.