Table 1. Summary of results for SNPs associated with pre-treatment pain in HNSCC patients.
SNP | Chr. | Gene | Location (bp)* | MAF | Minor allele | Genetic model | Discovery phase |
Replication phase |
Combined |
|||
---|---|---|---|---|---|---|---|---|---|---|---|---|
OR (95% CI) | P | OR (95% CI) | P | OR (95% CI) | P | |||||||
rs3862188 | 1 | RP11-634B7.4 | 247865773 | 0.28 | G | ADD | 1.73 | 7.35E-05 | 2.24 | 1.49E-03 | 1.87 | 3.45E-08 |
(1.32–2.26) | (1.36–3.68) | (1.50–2.33) | ||||||||||
rs880143 | 1 | RP11-634B7.4 | 247868113 | 0.28 | G | ADD | 1.73 | 7.35E-05 | 2.24 | 1.49E-03 | 1.87 | 3.45E-08 |
(1.32–2.26) | (1.36–3.68) | (1.50–2.33) | ||||||||||
rs7526880 | 1 | RP11-634B7.4 | 247862621 | 0.28 | G | ADD | 1.72 | 1.03E-04 | 2.24 | 1.49E-03 | 1.87 | 4.92E-08 |
(1.31–2.26) | (1.36–3.68) | (1.49–2.33) |
*Human annotation release 105.