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. 2016 Sep 26;35:151. doi: 10.1186/s13046-016-0422-z

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© The Author(s). 2016

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 3 — Increased tumorous AREG expressing was associated with poor prognosis and with increased HBGEF expression. a Whereas only 7.5 % (3/40) of cis-/carbo-platin treated patients with lower than median tumorous AREG mRNA levels died within 20 months, 26.7 % (8/30) patients with higher levels died (Kaplan-Meier curve, Log rank test, p = 0.007). b Tumorous AREG mRNA expression was correlated to HBGEF mRNA expression, only (p < 0.001; r = 0.54, Spearman correlation analysis)