Table 1.

Neutralization sensitivity (IC₅₀) of BaL (tier 1), JR-FL (tier 2), and C34r mutants by purified IgG from HIV-1 infected patients

Patient ID	IC50 (µg/mL)
	BaL	JR-FL	C34r
Patient 1	27	>300	>300
Patient 2	119	>300	74
Patient 3	114	>300	190
Patient 4	46	240	61
Patient 5	124	>300	>300
Patient 6	>300	>300	>300
Patient 7	178	>300	8.4
Patient 8	11	30	48
Patient 9	6	66	46
Patient 10	18	>300	161
KTS376	9	45	70
Total neutralized	91 %	36 %	73 %

IC₅₀ of purified IgGs from HIV-1 infected patients against pseudoviruses with envelope from BaL, JR-FL (WT) and C34-resistant mutants were measured using TZM-bl cells