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Phage homing to atherosclerotic lesions at aortic root of LDLr−/− mice.
| Phages/Control | LDLr−/− High-Fat Diet | LDLr−/− Regular-Diet |
|---|---|---|
| CTHRSSVVC-phage * | 100% (n = 6) | 0% (n = 4) |
| Insertless phage (Fd) | 0% (n = 6) | 0% (n = 3) |
| Vehicle Total | 0% (n = 1) (n = 13) | 0% (n = 1) (n = 8) |
LDLr−/− were fed High-Fat or Regular diet. * p < 0.01 compared to Regular-diet by Fisher’s test CTHRSSVVC-phage * to LDLr−/− mice High-Fat diet homing 100% positivity.
