Table 5.
Drug | SNP | SNP Loci | Gene ID | Target | Base Mutation | Amino Acid Mutation | Previously Reported |
---|---|---|---|---|---|---|---|
INH a | rs_5245 | 2154724 | Rv1908c | KatG | CGG > CTG | R463L | [19] |
EMB b | rss_17410 | 4247709 | Rv3795 | embB | AAC > ACC | N399T | – |
EMB b | rss_17411 | 4247729 | Rv3795 | embB | GGC > AGC | G406S | [16,21] |
ETH c | rss_8886 | 2154724 | Rv1908c | KatG | CGG > CTG | R463L | – |
ETH c | rss_8900 | 2155648 | Rv1908c | KatG | TAC > TGC | Y155C | [16] |
a isoniazid; b ethambutol; c ethionamide.