Table 1.
Immune system processing related differential proteins (21proteins).
| Protein (Acc.#) | LTB | EVP1 | LTB + EVP1 | Functions |
|---|---|---|---|---|
| A2MP (Q6GQT1) | 12.2462 | 2.1478 | 0.6607 | It is able to bind endogenous or foreign peptides, providing a barrier against pathogens. |
| * ARHGEF6 (Q8K4I3) | 1.6904 | 1.2474 | 1.6904 | Acts as a RAC1 guanine nucleotide exchange factor (GEF) and positive regulates immune responses. |
| AHSA2 (Q8N9S3) | 2.1677 | 2.1281 | 1.5704 | Cochaperone that stimulates HSP90 ATPase activity and stimulates antigen presentation through the class II pathway. |
| * EDIL3 (O35474) | 2.2699 | 0.4742 | 1.7219 | An important endogenous inhibitor of inflammatory cell adhesion and homing. |
| FCGR1 (P26151) | 2.0512 | 3.1046 | 2.1086 | Functions in both innate and adaptive immune responses. |
| GSTO1 (O09131) | 0.3981 | 0.2858 | 0.6427 | Exhibits glutathione-dependent thiol transferase and dehydroascorbate reductase activities. |
| HSPA4 (Q3U2G2) | 0.4487 | 0.1754 | 0.7178 | Involved in the antigen presentation and cross-presentation for specific triggering of the acquired immune response. |
| IFI35 (Q9D8C4) | 1.3932 | 0.6081 | 0.4246 | Interferon-induced protein 35 and negatively regulated RIG-I antiviral signaling. |
| OASL1 (Q8VI94) | 3.3113 | 3.1623 | 2.0701 | May play a role in mediating resistance to virus infection, control of cell growth, differentiation, and apoptosis. |
| OASL2 (Q9Z2F2) | 2.466 | 2.3768 | 1.4322 | May play a role in mediating resistance to virus infection, control of cell growth, differentiation, and apoptosis. |
| OAS1A (P11928) | 1.977 | 1.6293 | 1.556 | May play a role in mediating resistance to virus infection, control of cell growth, differentiation, and apoptosis. |
| OAS3 (Q8VI93) | 1.7061 | 1.3305 | 1.2023 | May play a role in mediating resistance to virus infection, control of cell growth, differentiation, and apoptosis. |
| PRDX1 (P35700) | 0.1888 | 0.0738 | 0.4699 | Reduces peroxides with reducing equivalents provided through the thioredoxin system but not from glutaredoxin. |
| S100A11 (P50543) | 0.1445 | 0.0649 | 0.2228 | Facilitates the differentiation and the cornification of keratinocytes and resists to virus infection. |
| * SLFN2 (Q9Z0I6) | 2.208 | 1.2023 | 1.6144 | May have a role in hematopoeitic cell differentiation, induction of immune responses. |
| SLFN5 (Q8CBA2) | 7.8705 | 6.6681 | 3.8371 | May have a role in hematopoeitic cell differentiation, induction of immune responses. |
| SLC11A2 (P49282) | 1.3183 | 2.421 | 1.4322 | May play an important role in hepatic iron accumulation and tissue iron distribution. |
| SLC27A4 (Q91VE0) | 1.1695 | 1.977 | 1.5704 | Plays a role in the formation of the epidermal barrier. Required for fat absorption in early embryogenesis. |
| STAU2 (Q8CJ67) | 1.0864 | 1.4723 | 1.8535 | RNA-binding protein, mRNA stability, translation. |
| STAT1 (Q8C3V4) | 2.466 | 2.2284 | 1.8197 | Transcription factor that binds to the IFN-stimulated response element (ISRE) and to the GAS element. |
| SWAP70 (Q6A028) | 1.5996 | 0.8872 | 1.3428 | Restricts spontaneous maturation of dendritic cells. |
0.5001–1.4999 means no variation and marked with boldface. The stars (*) marked the differential proteins expression which was significantly upregulated in both groups of LTB and LTB plus EVP1 without significant variation in group EVP1.