Figure 5.

Caspase-3 siRNAs blocked anti-miR-378-mediated neuronal injury in N2A cells. (A,B) Caspase-3 siRNA, but not its negative control effectively decreased caspase-3 protein expression in normoxia and OGD-treated groups, * p < 0.05 vs. non-OGD vehicle, # p < 0.05 vs. OGD vehicle, n = 3 per group; (C) MTT results showed that caspase-3 siRNAs had the ability to block anti-miR-378-mediated neuronal injury induced by OGD treatment, * p < 0.05 vs. OGD, # p < 0.05 vs. caspase-3 siRNA ctrl, n = 6 per group.