Figure 4.

Effect of LX519290 against pro-oxidant challenge in RAW264.7 cells. RAW264.7 cells were split and seeded at a density of 5 × 10⁴ cells per well (96-well plate) and measured ROS generation (A); total thiol content (B); glutathione S-transferases (GST) activity (C); and its mRNA expression (D) which were conducted with various concentrations of LX519290. ^## p < 0.01 indicates a significant difference from the no treatment group; * p < 0.05 and ** p < 0.01 indicate a significant difference from the H₂O₂-treated group.