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. 2016 Sep 1;17(9):1451. doi: 10.3390/ijms17091451

Figure 6.

Figure 6

The ORAC activity in the plasma after intraperitoneal injection of LX519290. (A) Rats were randomly divided into four groups (n = 5 rats per group): a normal group (saline), negative control group (AAPH, 50 mg/kg body weight), positive control group (ascorbic acid, 150 mg/kg body weight), and LX519290 group (15 mg/kg body weight). ** p < 0.01, significantly different from AAPH-treated group, using a one-way ANOVA followed by Tukey’s post hoc test. Analysis of mRNA levels of NAD(P)H:quinone oxidoreductase1 (NQO1), glutathione peroxidase (GPx), superoxide dismutase (SOD), and catalase (CAT) in liver tissue. Male Wistar rats, aged 7–8 weeks and weighing 230–270 g (Samtaco Korea, Osan, Korea), were administered intraperitoneal AAPH with LX519290 for 10 days. The liver was excised from each animal, and the mRNA level of NQO1 (B); GPx (C); SOD (D); and CAT (E) was measured by RT-PCR. * p < 0.05, ** p < 0.01 indicates a significant difference from the AAPH-treated group, using a one-way ANOVA followed by Tukey’s post hoc test.