Table 1.
Characteristics of study population in AMORIS, overall, and for the lowest and highest serum calcium quartiles.
| Serum Calcium (mmol/L) | |||
|---|---|---|---|
| All (n = 229,674) | Q1 < 2.31 (n = 55,357) | Q4 ≥ 2.44 (n = 59,462) | |
| Age (years) Mean (SD) | 46.16 (15.19) | 44.49 (13.72) | 48.82 (16.25) |
| SES | |||
| High | 82,555 (35.94) | 21,707 (39.21) | 18,882 (31.75) |
| Low | 116,202 (50.59) | 27,295 (49.31) | 31,084 (52.28) |
| Unclassified | 30,917 (13.46) | 6355 (11.48) | 9496 (15.97) |
| Education Status | |||
| High | 56,856 (24.76) | 15,649 (28.27) | 12,233 (20.57) |
| Middle | 98,268 (42.79) | 23,918 (43.21) | 24,631 (41.42) |
| Low | 62,456 (27.19) | 13,182 (21.81) | 18,775 (31.57) |
| Missing | 12,094 (5.27)) | 2608 (4.71) | 3823 (6.43) |
| Parity | |||
| Yes | 155,706 (67.79) | 38,594 (69.72) | 40,094 (67.43) |
| No | 73,968 (32.21) | 16,763 (30.28) | 19,368 (32.57) |
| Breast Cancer | |||
| Yes | 10,863 (4.73) | 2656 (4.80) | 2829 (4.76) |
| No | 218,811 (95.27) | 52,701 (95.20) | 56,633 (95.24) |
| Calcium (mmol/L) Mean (SD) | 2.38 (0.10) | 2.26 (0.04) | 2.50 (0.06) |
| Corrected Calcium (mmol/L) Mean (SD) | 2.32 (0.09) | 2.23 (0.06) | 2.43 (0.08) |
| Albumin (g/L) Mean (SD) | 42.50 (2.74) | 41.15 (2.65) | 43.76 (2.64) |
| Charlson Comorbidity Index | |||
| 0 | 213,122 (92.79) | 51,713 (93.42) | 54,205 (91.16) |
| 1 | 8819 (3.84) | 2023 (3.65) | 2712 (4.56) |
| 2 | 5692 (2.48) | 1155 (2.09) | 1870 (3.14) |
| 3+ | 2041 (0.89) | 466 (0.84) | 675 (1.14) |
| History of Fractures | |||
| Yes | 173 (0.08) | 45 (0.08) | 43 (0.07) |
| No | 229,501 (99.92) | 55,313 (99.92) | 59,419 (99.93) |
| Seasonality | |||
| Spring | 66,166 (28.81) | 16,150 (29.17) | 17,455 (29.35) |
| Summer | 37,733 (16.43) | 8996 (16.25) | 10,150 (17.07) |
| Autumn | 68,503 (29.83) | 16,620 (30.02 | 16,924 (28.46) |
| Winter | 57,272 (24.94) | 13,591 (24.55) | 14,933 (25.11) |
| Follow-up (years) Mean (SD) | 19.40 (5.91) | 19.58 (5.75) | 18.99 (6.31) |