(A) Receiver operating characteristics (ROC) curves of Wisteria floribunda agglutinin-positive Mac-2-binding protein (WFA+-M2BP) for survival in all cases (n = 165). The optimal cutoff point for WFA+-M2BP level was 6.15 cutoff index (COI) (annual area under the ROC (AUROC) = 0.79348, sensitivity = 80.0%, specificity = 74.78%); (B) Cumulative overall survival stratified by WFA+-M2BP in all cases. The cumulative one-, three- and five-year survival rates were: 86.96%, 60.14% and 43.99%, respectively, in patients with WFA+-M2BP ≥ 6.15 COI (n = 69), while 94.76%, 92.41% and 88.40%, respectively, in patients with WFA+-M2BP < 6.15 COI (n = 96) (p < 0.0001).