Figure 2.

Comparison of anti-GRP78 and anti-carbamylated GRP78 (CarGRP78) antibody levels in the sera from controls, and patients with rheumatoid arthritis (RA), systemic lupus erythematosus (SLE) or primary Sjögren syndrome (pSS). (A) We observed no significant differences in anti-GRP78 antibody levels in the serum between patients with RA, SLE or pSS and controls; (B) Patients with RA but not SLE or pSS had significantly higher sera titers of anti-CarGRP78 antibodies compared with controls. O.D., optical density. The cutoff values for the anti-GRP78 and anti-CarGRP78 antibody ELISA was defined as the mean plus two standard deviations of the controls.