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. 2016 Sep 14;17(9):1545. doi: 10.3390/ijms17091545

Table 1.

The cutoff value and diagnostic ability of each fibrosis marker in NAFLD patients.

NAFLD (n = 58)
Fibrosis Markers Cutoff AUROC Sensitivity Specificity
WFA+-M2BP C.O.I 1.06 0.70 75 67
TIMP-1 ng/mL 242.0 0.50 50 68
HA ng/mL 58.9 0.87 80 86
PIIIP ng/mL 11.4 0.58 50 74
Platelet count ×104/μL 17.7 0.74 67 80
FIB-4 Index 1.95 0.77 67 78
APRI 3.25 0.62 50 70
AST/ALT ratio 0.82 0.75 75 78
ICG-R15 % 10.5 0.74 67 64

Stage 0–2 (n = 46) vs. Stage 3–4 (n = 12). AUROC, area under the receiver operating characteristic curve; NAFLD: nonalcoholic fatty liver disease.