Figure 5.
Stimulated astrocytes by MSCs released angiogenic factors: (A) representative images of Western blot analysis; (B,C) when astrocytes co-cultured with MSCs were cultured, angiogenic factors, such as ANGPT1 and ANGPT2, were significantly increased compared to cultured astrocytes alone and cultured MSCs alone (** p < 0.01 and *** p < 0.001, respectively, n = 3 each); and (D) the astrocytes co-cultured with MSCs and astrocytes cultured alone increased the expression of GFAP compared with MSCs groups (*** p < 0.001, n = 3 each). Values represent mean + SEM.