Figure 6.

The combination of MSCs and EE synergistically improved motor function. (A–F) The rotarod tests were performed at two and eight weeks post-treatment; (A–C) Two weeks after treatment, MSC-EE mice expressed a tendency to exhibit enhanced motor function, but no significant differences were observed among the groups; (D–F) Eight weeks after the treatment, the rotarod tests at constant (48 and 64 rpm) and accelerating (4–80 rpm) speeds showed that the MSC-EE mice were significantly improved compared to those of MSC-CON and PBS-CON (* p < 0.05, ** p < 0.01, and *** p < 0.001, n = 15 each). Values represent mean + SEM.