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. 2016 Sep 21;17(9):1592. doi: 10.3390/ijms17091592

Table 3.

The McDonald criteria compared.

Classification McDonald Criteria McDonald Criteria Pleocytosis (≥5 cells/µL) Intrathecal Synthesis CSF Oligoclonal Bands
IgM IgG IgA
Multiple sclerosis 2005/2001 70 66% 37% 64% 16% 98.5%
2010 136 65% 35% 63% 13% 96%
p value - p = 0.0001 p = 1.0 p = 0.9 p = 1.0 p = 0.7 p = 0.4
Clinically isolated syndrome 2005/2001 255 55% 19% 40% 6% 65%
2010 189 52% 14% 33% 4% 55%
p value - p = 0.0001 p = 0.8 p = 0.4 p = 0.4 p = 0.7 p = 0.2

Cerebrospinal fluid findings in patients with multiple sclerosis and clinically isolated syndrome according to the McDonald criteria 2010 in comparison to the McDonald criteria 2005/2001.