Table 3.
Classification | McDonald Criteria | McDonald Criteria | Pleocytosis (≥5 cells/µL) | Intrathecal Synthesis | CSF Oligoclonal Bands | ||
---|---|---|---|---|---|---|---|
IgM | IgG | IgA | |||||
Multiple sclerosis | 2005/2001 | 70 | 66% | 37% | 64% | 16% | 98.5% |
2010 | 136 | 65% | 35% | 63% | 13% | 96% | |
p value | - | p = 0.0001 | p = 1.0 | p = 0.9 | p = 1.0 | p = 0.7 | p = 0.4 |
Clinically isolated syndrome | 2005/2001 | 255 | 55% | 19% | 40% | 6% | 65% |
2010 | 189 | 52% | 14% | 33% | 4% | 55% | |
p value | - | p = 0.0001 | p = 0.8 | p = 0.4 | p = 0.4 | p = 0.7 | p = 0.2 |
Cerebrospinal fluid findings in patients with multiple sclerosis and clinically isolated syndrome according to the McDonald criteria 2010 in comparison to the McDonald criteria 2005/2001.