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. Author manuscript; available in PMC: 2017 Oct 15.
Published in final edited form as: Toxicol Appl Pharmacol. 2016 Sep 7;309:141–148. doi: 10.1016/j.taap.2016.09.002

Figure 2.

Figure 2

Diets supplemented with fish oil, but not soybean oil prevents mercury from interfering with SEB dependent activation of caspase 8 in CD8 and CD4 positive T cells. Blue checkered bars indicate results from mice maintained on the soy oil enriched diet that were inoculated with SEB (positive controls). Red cross-hatched bars represent results from mice on either the soy oil or fish oil diets that were stimulated with SEB and exposed to Hg. Solid blue bars represent results from mice on either the soy or fish oil diets that were not stimulated with SEB and not exposed to Hg (negative controls). Error bars represent SEM; * indicates statistically significant difference in SEB dependent caspase 8 activation in T cells from mercury exposed mice maintained on fish oil enriched diets vs diets enriched with soybean oil. (A) Difference (MFI) between SEB dependent caspase 8 activation in CD8+, Vβ8+ and Vβ6+ T cells. * p < .003. (B) Difference (Overton subtraction) between SEB dependent caspase 8 activation in CD8+, Vβ8+ and Vβ6+ T cells. *p < .030 (C) Difference (MFI) between SEB dependent caspase 8 activation in CD4+, Vβ8+ and Vβ6+ T cells. *p < .006 (D) Difference (MFI) between SEB dependent caspase 8 activation in CD8+, Vβ8+ and Vβ6+ T cells. *p < .007