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. 2016 Sep 26;4(18):e12863. doi: 10.14814/phy2.12863

Figure 1.

Figure 1

Chow‐fed MIP‐CreER mice have enhanced β‐cell mass due to increased β‐cell size. (A) β‐cell mass, (B) β‐cell proliferation, (C) β‐cell size, (D) β‐cell number, (E) percentage of small insulin+ clusters, and (F) Intraperitoneal glucose tolerance tests (IP‐GTT) and area under the curve (AUC) of IP‐GTT for chow‐fed 8‐week‐old WT (n = 5) or MIP‐CreER (n = 5) male mice. Black boxes represent WT mice; open boxes represent MIP‐CreER mice. Data are shown as means ± SEM. P values were calculated using Student's t‐test for (A–C), (E) and two‐way ANOVA followed by Tukey post hoc analysis for D. *P = 0.02 in (A); **P = 0.0081 in (C).