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. 2016 Sep 26;4(18):e12968. doi: 10.14814/phy2.12968

Figure 5.

Figure 5

Atrial natriuretic peptide (ANP; 100 nmol/L) did not attenuate the increase in apparent albumin permeability (measured as peak response of Hist w/ANP relative to Hist alone) in response to histamine in individually perfused rat mesentery microvessels (n = 16 ctrl, n = 8 Hist w/ANP, n = 8 Hist, P = 0.64; Mann–Whitney). The perfusate in these vessels was a standard Ringer‐albumin solution containing red cell (1.5% to ensure a stable baseline permeability; Curry et al. 2012) but no polymorphonuclear leukocytes.