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. 2016 Sep 27;7:342. doi: 10.3389/fphar.2016.00342

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Copyright © 2016 Abboud, Mi, Puccio, Okonkwo, Buliga, Constantine and Vodovotz.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Initial GCS scores could not segregate patients for mortality vs. survival. An initial GCS score was calculated following the traumatic insult. The GOS score was utilized as the outcome variable and was viewed as the response variable. The GOS score quantifies the neurological outcome at 6 and 12 months post-TBI. GOS scores ranged from 1 to 5, with 1 indicating death and higher values indicating a progressively better neurological state of health. There were no statistical differences in the mean GCS between survivors (6.0 ± 0.24) and non-survivors (5.6 ± 0.57, p = 0.313). Furthermore, a plot of GCS vs. GOS was unable to cluster those who went onto survive (GOS > 1) from those who died (GOS = 1). These findings highlight the inutility of GCS alone in predicting patient outcomes.