TABLE 2.
Genes, predicted amino acid lengths, and putative functions of the monocin gene cluster
| ORFa | Gene designation | Product length (aa) | Putative product function | Phage A118 homologue (% aa identity) | Comment |
|---|---|---|---|---|---|
| 0125 | ftbA | 231 | Transcriptional regulator | ||
| 0126 | ftbB | 150 | Toxin/antitoxin | gp35 (46) | |
| 0127 | ftbC | 117 | Toxin/antitoxin, lambda C1, HTH | ||
| 0128 | ftbD | 142 | Antigen D (unknown function) | gp61 (46) | |
| 0129 | ftbE | 138 | Antigen C/transcriptional regulator | gp66 (39) | |
| 0130 | ftbF | 129 | Antigen B (unknown function) | ||
| 0131 | ftbG | 170 | Antigen A major phage tail | gp12 (15) | Strong similarity to several putative TP901-1-like prophage major tail proteins among diverse bacteria |
| 0132 | ftbH | 100 | Hypothetical phage-related protein | ||
| 0133 | ftbI | 130 | Hypothetical phage-related protein | ||
| 0134 | ftbJ | 622 | Tape measure | gp16 (19) | Less than half the length of the A118 tape measure |
| 0135 | ftbK | 272 | Phage tail component | gp17 (36) | |
| 0136 | ftbL | 378 | Phage tail component | gp18 (33) | |
| 0137 | ftbM | 99 | Hypothetical phage-related protein | ||
| 0138 | ftbN | 191 | Hypothetical phage-related protein | Potential peptidase | |
| 0139 | ftbO | 159 | Hypothetical phage-related protein | ||
| 0140 | ftbP | 178 | Receptor binding | gp20 | 50% identity between aa 36 to 68 and A118 gp20 |
| 0141 | ftbQ | 140 | Holin | ||
| 0142 | ftbR | 242 | Lysin |
a
The ORF numbering system is based on strain F6854.