FIG 2.

Metabolic routes for the production of isoprenoid-based biofuels in a living system. The mevalonate (MVA) pathway is from acetyl-CoA, and the deoxyxylulose 5-phosphate (DXP) pathway is from glyceraldehyde-3-phosphate and pyruvate. IPP, isoprenyl diphosphate; DMAPP, dimethylallyl diphosphate; IDI, isoprenyl diphosphate isomerase; nudiX, nucleoside diphosphate hydrolases; GPP, geranyl pyrophosphate; FPP, farnesyl pyrophosphate; GPPS, geranyl pyrophosphate synthase; FPPS, farnesyl pyrophosphate synthase; PS, pinene synthase; FS, farnesene synthase; BS, bisabolene synthase; PPS, endogenous pyrophosphatase.