FIG 3.

Serum S. epidermidis-specific IgG1, IgG2a, and IgG3 levels detected in S. epidermidis-immunized and -challenged mice given the immunization-and-challenge combination 9142/S-9142, M10/S-9142, or PBS/S-9142. IgG titers were determined in serum samples collected 4 days after i.v. infection with isopropanol-fixed S-9142 cells as the antigen to coat ELISA plates. Data are presented as log₁₀ antibody titers, as indicated. Results correspond to pooled data of three independent experiments. Each dot represents an individual mouse. The horizontal line in each group represents the mean value. One-way ANOVA, P < 0.05, with Tukey's post hoc test: *, P < 0.05; **, P < 0.01; ***, P < 0.001.