Table V.

Top five enriched gene ontology terms in biological process, cellular component and molecular function categories for DEGs in module 1.

A, Biological process
GO_ID	Term	Count	P-value	DEG
GO:0007229	Integrin-mediated signaling pathway	7	1.34×10−14	ITGB6, BCAR1, ITGA6, ITGB4, ITGB5, ITGA3, ITGB8
GO:0030198	Extracellular matrix organization	7	3.66×10−10	ITGB6, LAMA3, ITGA6, ITGB4, ITGB5, ITGA3, ITGB8
GO:0043062	Extracellular structure organization	7	3.73×10−10	ITGB6, LAMA3, ITGA6, ITGB4, ITGB5, ITGA3, ITGB8
GO:0007155	Cell adhesion	8	1.30×10−8	ITGB6, BCAR1, LAMA3, ITGA6, ITGB4, ITGB5, ITGA3, ITGB8
GO:0022610	Biological adhesion	8	1.35×10−8	ITGB6, BCAR1, LAMA3, ITGA6, ITGB4, ITGB5, ITGA3, ITGB8
B, Cellular component
GO_ID	Term	Count	P-value	DEG
GO:0008305	Integrin complex	6	3.33×10−15	ITGB6, ITGA6, ITGB4, ITGB5, ITGA3, ITGB8
GO:0098636	Protein complex involved in cell adhesion	6	3.33×10−15	ITGB6, ITGA6, ITGB4, ITGB5, ITGA3, ITGB8
GO:0043235	Receptor complex	6	2.87×10−9	ITGB6, ITGA6, ITGB4, ITGB5, ITGA3, ITGB8
GO:0030055	Cell-substrate junction	6	2.02×10−8	BCAR1, VASP, ITGA6, ITGB4, ITGB5, ITGA3
GO:0009986	Cell surface	6	4.88×10−7	ITGB6, ITGA6, ITGB4, ITGB5, ITGA3, ITGB8
C, Molecular function
GO_ID	Term	Count	P-value	DEG
GO:0005178	Integrin binding	4	3.15×10−7	ITGB6, ITGA6, ITGB5, ITGA3
GO:0050839	Cell adhesion molecule binding	4	2.35×10−6	ITGB6, ITGA6, ITGB5, ITGA3
GO:0005102	Receptor binding	7	2.36×10−6	ITGB6, LAMA3, ITGA6, ITGB4, ITGB5, ITGA3, ITGB8
GO:0043236	Laminin binding	2	1.47×10−4	ITGA6, ITGA3
GO:0050840	Extracellular matrix binding	2	4.39×10−4	ITGA6, ITGA3

GO, gene ontology; DEGs, differentially expressed genes.