Table I.
Enriched KEGG pathways of differentially-expressed genes.
KEGG pathways | Gene count | P-value |
---|---|---|
Upregulated genes | ||
Ribosome | 12 | 1.45×10−5 |
Focal adhesion | 18 | 2.21×10−5 |
ECM-receptor interaction | 10 | 1.85×10−4 |
Shigellosis | 8 | 3.91×10−4 |
Adherens junction | 8 | 1.32×10−3 |
Regulation of actin cytoskeleton | 14 | 4.10×10−3 |
Pathogenic Escherichia coli infection | 6 | 5.92×10−3 |
Colorectal cancer | 6 | 9.68×10−3 |
Downregulated genes | ||
Calcium signaling pathway | 8 | 6.10×10−4 |
Cytokine-cytokine receptor interaction | 9 | 2.11×10−3 |
Neuroactive ligand-receptor interaction | 9 | 2.52×10−3 |
Dilated cardiomyopathy | 5 | 2.84×10−3 |
Arachidonic acid metabolism | 4 | 3.73×10−3 |
Pancreatic secretion | 5 | 4.66×10−3 |
Gene count represents the number of genes enriched in the KEGG pathway. KEGG, Kyoto Encylopedia of Genes and Genomes; ECM, extracellular matrix.