Table IV.
Studies included in the locoregional recurrence analysis of the effect of PMRT on breast cancer patients with 1–3 positive lymph nodes.
| First author, year (Refs.) | Country | Study design | Number of participants (total) | Number in control group | Number in intervention group | Type of surgery | Median age (years) | Median follow-up (months) | Locoregional recurrence rate, control group, n (%) | Locoregional recurrence rate, intervention group, n (%) |
|---|---|---|---|---|---|---|---|---|---|---|
| Kong, 2013 (5) | Korea | Retrospective case series | 110 | 78 | 32 | Mastectomy | 48.6 | 84 | 10 (12.8) | 2 (6.2) |
| Cosar, 2011 (7) | Turkey | Retrospective case series | 90 | 24 | 66 | Mastectomy | 51 | 72 | 4 (17) | 2 (3.0) |
| Ragaz,1997 (9) | Canada | Randomised controlled trial | 183 | 92 | 91 | Mastectomy | NR | 150 | 15 (16.0) | 6 (7.0) |
| Su, 2014 (10) | Taiwan | Retrospective case series | 207 | 126 | 81 | Mastectomy | 50 | 59.5 | 15 (11.8) | 4 (4.7) |
| Moo, 2013 (11) | USA | Retrospective case series | 1,087 | 924 | 163 | Mastectomy | NR | 84 | 40 (4.3) | 5 (3.2) |
| Huang, 2012 (12) | China | Retrospective case series | 318 | 155 | 163 | Mastectomy | 48.5 (mean) | 102 | 17 (11.0) | 5 (3.1) |
| He, 2015 (13) | China | Retrospective case series | 697 | 618 | 79 | Mastectomy | NR | 65 | 65 (10.5) | 1 (1.3) |
| Tendulkar, 2012 (14) | America | Retrospective case series | 369 | 271 | 98 | Mastectomy | 56 | 62.4 | 24 (8.9) | 0 (0.0) |
| McBride, 2014 (15) | USA | Retrospective case series | 1,027 | 800 | 235 | Mastectomy | NR | 144.5 | 71 (8.9) | 11 (4.7) |
| Harris, 2013 (16) | USA | Retrospective case series | 250 | 204 | 46 | Mastectomy | NR | 65.6 | 13 (6.4) | 1 (2.2) |
| Overgaard, 1997 (17) | Denmark | Randomised controlled trial | 1,061 | 516 | 545 | Mastectomy | NR | 114 | 155 (30.0) | 38 (7.0) |
PMRT, post-mastectomy radiotherapy; NR, not reported.