Table II.
Correlation between CD168 OE and clinicopathological parameters of 78 colorectal patients.
| CD168 OE | |||
|---|---|---|---|
| Parameter | (−), n | (+), n | P-value |
| Gender | 0.04 | ||
| Male | 46 | 6 | |
| Female | 18 | 8 | |
| Age, years | 0.62 | ||
| <65 | 34 | 7 | |
| ≥65 | 29 | 8 | |
| Tumor location | 0.20 | ||
| Colon | 29 | 9 | |
| Rectum | 35 | 5 | |
| Histological differentiation | 0.41a | ||
| Well-differentiated | 25 | 1 | |
| Moderately-differentiated | 27 | 9 | |
| Poorly-differentiated | 12 | 4 | |
| Tumor stage | 0.67b | ||
| T1 | 1 | 0 | |
| T2 | 6 | 1 | |
| T3 | 24 | 6 | |
| T4 | 33 | 7 | |
| Lymph node involvement | 0.78c | ||
| N0 | 34 | 8 | |
| N1 | 22 | 2 | |
| N2 | 8 | 4 | |
| Metastasis | 0.23 | ||
| M0 | 60 | 13 | |
| M1 | 4 | 1 | |
| TNM staged | 0.78e | ||
| I | 4 | 1 | |
| II | 30 | 7 | |
| III | 26 | 5 | |
| IV | 4 | 1 | |
a
Well- and moderately-differentiated vs. poorly-differentiated.
b
T1+T2 vs. T3+T4.
c
N0 vs. N1+N2.
d
aAmerican Joint Committee on Cancer staging system.
e
I+II vs. III+IV. (−), negative overexpression; (+), positive overexpression; CD168, cluster of differentiation 168; OE, overexpression; TNM, tumor-node-metastasis.