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. 2016 Jul 27;12(4):2567–2573. doi: 10.3892/ol.2016.4914

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Figure 4. — Impact of miR-486-5p on cellular migration. (A) Representative images taken of scratches at the 0 and 24 h time points. Areas of scratches were measured using Zen2012 software. Cellular migration was calculated as the percentage of wound closure. (B) Similar to the positive control knockdown cells transfected with IGF-1R siRNAs, miR-486-5p mimic cells showed a significant reduction in tumor cell migration compared with the mock cells (P=0.0286). *P<0.05. siRNA, small interfering RNA; IGF-1R, insulin-like growth factor 1 receptor; miR, microRNA.