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. 2016 Sep 23;60(10):5627–5630. doi: 10.1128/AAC.00705-16

TABLE 2.

Calculations of %fT>MIC values of simulated ceftolozane-tazobactam dosing regimens

Dose (duration of intravenous infusion) %fT>MIC against MIC (μg/ml):
0.5 1 2 4 8
1.5 g q8h (1 h) 100 97.50 83.75 70 56.3
1.5 g q8h (3 h) 100 100 98.75 84.6 69.6
1.5 g q6h (1 h) 100 100 100 94.6 76.3
1.5 g q6h (3 h) 100 100 100 99.6 95.4
3 g q8h (1 h) 100 100 100 92.5 78.8
3 g q8h (3 h) 100 100 100 100 93.8