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MB17 induces DNA fragmentation. (a) Control cells and cells treated with MB17 (IC50) or MB17 (IC80) were subjected to a TUNEL assay (red) and stained with DAPI (blue). White asterisks indicate TUNEL-positive kinetoplasts, and yellow asterisks indicate TUNEL-positive nuclei. N, nucleus; k, kinetoplast. Bar, 2 μm. (b) The percentage of TUNEL-positive nuclei or kinetoplasts was plotted after analysis of 100 cells from each treatment.
