TABLE 6.

In vitro frequencies of resistance^a

Compound	Resistance frequency at:
	4× MIC	10× MIC
Compound 14	4.6 × 10−6	3.9 × 10−6
Isoniazid	ND	1.8 × 10−5
Moxifloxacin	1.7 × 10−7	1.1 × 10−8

^aThe MIC values for compound 14, isoniazid, and moxifloxacin on Middlebrook 7H10 agar were determined to be 0.2, 0.06, and 0.08 μg/ml, respectively. ND, not determined.