TABLE 1.
Sources and MICs for the two mcr-1-positive E. coli isolates, their transformants, and the recipient strain
| Isolate | Country | Time of isolation | Source | ST | MIC (mg/liter)a |
|||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AMP | GEN | CIP | NAL | TMP | MEM | TET | CTX | CHL | TGC | CAZ | CST | |||||
| BB1290 | Venezuela | August 2015 | Human feces | 19 | >64 | >32 | >8 | >128 | >32 | 8 | >64 | >4 | >128 | 1 | >8 | 4 |
| BB1290Tb | Laboratory | 4 | <0.5 | 0.06 | 64 | <0.25 | <0.03 | <2 | <0.25 | <8 | <0.25 | <0.5 | 4 | |||
| BB1291 | Venezuela | August 2015 | Swine feces | 452 | >64 | >32 | >8 | >128 | >32 | <0.03 | >64 | >4 | >128 | <0.25 | 4 | 4 |
| BB1291Tb | Laboratory | 4 | <0.5 | 0.06 | 64 | <0.25 | <0.03 | <2 | ≤0.25 | ≤8 | <0.25 | <0.5 | 4 | |||
| E. coli HST08 | Laboratory | 4 | <0.5 | 0.03 | 64 | <0.25 | <0.03 | <2 | <0.25 | <8 | <0.25 | <0.5 | <1 | |||
a
AMP, ampicillin; GEN, gentamicin; CIP, ciprofloxacin; NAL, nalidixic acid; TMP, trimethoprim; MEM, meropenem; TET, tetracycline; CTX, cefotaxime; CHL, chloramphenicol; TGC, tigecycline; CAZ, ceftazidime; CST, colistin. Resistance is highlighted in bold.
b
E. coli HST08 transformed with a mcr-1-bearing plasmid.