Skip to main content
. 2016 Sep 23;60(10):6216–6226. doi: 10.1128/AAC.00815-16

TABLE 6.

Persistence of NS5A RAMs through postdose week 12, 24, or 48

GT Dose Patient RAM(s) persistent up to wk 48 (%)a
1a 10 5306 UNK
10 5310 Q30H(1)/R(37), L31M(43), H58D(2), Y93N(7)/C(8)
10 5314 Q30H(56)/R(13), F36L(1)
10 5407b K24R(2), M28V(66), Q30H(8)/R(80), L31M(2), H58C(15)/D(2), Y93F(12)
30 5303 Q30H(14)/R(79), H58D(3)
30 5307 ND
30 5313 UNK
100 5301 M28T(2), L31M(77)
100 5308 M28T(5)/V(4), Q30H(2)/R(78), L31M (1), Y93C(2)
100 5311c M28T(63), Q30R(53)
200 5304 UNK
200 5305 UNK
200 5309 UNK
1b 10 5404 UNK
10 5409 ND
30 5405 Y93H(3)
30 5413c ND
30 5414 Y93H(99)
100 5402 L28 M(6), R30Q(16), L31 M(35), Y93H(37)/N(45)
100 5406b R30G(3), L31V(46)/M(2), Y93H(4)
100 5410 L31M(12), Y93H(10)
200 5403 UNK
200 5408c L31V(2)/M(97), Y93H(92)
200 5411b L28 M(58), R30Q(5)/H(95)
a

UNK, no data for week 12, 24, or 48; ND, no RAMs detected.

b

Week 12 persistence.

c

Week 24 persistence.