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Inhibitory effect (%) of GSL on the proliferation of PANC-1, AsPC-1 and C3H10T1/2 cells.
| Concentration of GSL, µM | ||||||
|---|---|---|---|---|---|---|
| Cells | 5 | 10 | 20 | GANT61a | IC50 values, µM | |
| PANC-1 | 48.8±2.1 | 62.4±3.2 | 70.0±4.1 | 82.2±1.7 | 6.9 | |
| AsPC-1 | 49.9±0.8 | 62.1±2.5 | 73.1±2.3 | 79.7±3.3 | 5.1 | |
| C3H10T1/2 | 17.0±1.5 | 27.8±1.1 | 35.3±2.5 | 60.8±2.8 | 35.7 | |
GANT61 (30 µM) was used as the positive control. GSL, germacranolide sesquiterpene lactone; IC50, 50% inhibitory concentration.
