Table III.
Comparison of performance characteristics of individual markers and a marker combination in predicting sepsis.
| Markers | Cut off | Sensitivity (%) | Specificity (%) | Accuracy (%) | PPV (%) | NPV (%) | Youden's index (%) |
|---|---|---|---|---|---|---|---|
| PCT | 0.37 | 91.70 | 69.50 | 80.60 | 75.00 | 89.34 | 61.20 |
| CRP | 126.25 | 53.30 | 79.70 | 66.50 | 72.40 | 63.10 | 33.00 |
| RDW | 13.45 | 73.30 | 49.20 | 61.20 | 59.10 | 64.80 | 22.50 |
| PDW | 13.35 | 38.30 | 84.70 | 61.50 | 71.50 | 57.90 | 23.10 |
| NLCR | 9.37 | 81.10 | 62.70 | 71.92 | 68.51 | 76.87 | 43.80 |
| Combination | – | 80.00 | 62.70 | 71.40 | 68.20 | 75.80 | 42.70 |
PPV, positive predictive value; NPV, negative predictive value; PCT, procalcitonin (ng/ml); CRP, C-reactive protein (mg/l); RDW, red blood cell distribution width (%); PDW, platelet distribution width (%); NLCR, neutrophil-lymphocyte count ratio (%); combination, RDW + PDW + NLCR.