Representative histopathologic condition of the terminal ileum from each experimental group stained with H&E (original magnification, ×10). Intestinal architecture of a rat from (A) the control group revealed normal histological findings; (B) NEC group and NEC group treated with (C) 25, (D) 50 and (E) 75 mg/kg AS-IV groups. H&E, hematoxylin and eosin; NEC, necrotizing enterocolitis; AS-IV, astragaloside IV.