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Mitochondria death pathway involvement of OMP31 in Brucella melitensis 16M. Transcriptional levels of (A) Bcl-2 and (B) Bax in RAW264.7 cells infected by B. melitensis 16MΔomp31 mutant or parent strain. (C) Cytochrome c (Cyt c) release from RAW264.7 cells infected by B. melitensis 16MΔomp31 mutant or parent strain. (D) Caspase-3 and −5 levels of RAW264.7 cells infected by B. melitensis 16MΔOMP31 mutant or parent strain. *P<0.05.
